CHOI, JUN WON,KIM, KYOUNGSUN,LEE, SI YOUNG,UM, TAE HEUM
申请号:
CA3054788
公开号:
CA3054788A1
申请日:
2017.08.04
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to a stabilized external use agent comprising thymosin beta-4 as an effective ingredient and, more particularly, to an external use agent having therapeutically effective Tß4 improved in biological activity and stability. Through the improvement, the external use according to the present invention can maintain the biological activity of Tß4 and minimize the generation of Tß4 sulfoxide attributed to an oxidation reaction and the generation of multimers attributed to aggregation, thereby providing Tß4 in a stable state.