Rafael V. Davalos,Paulo A. Garcia,John H. Rossmeisl,John L. Robertson,Robert E. Neal, II
申请号:
US16535451
公开号:
US20190376055A1
申请日:
2019.08.08
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.