Disclosed are: a para-terphenyl compound represented by the formula (1) or a pharmacologically acceptable salt thereof； a method for producing the para-terphenyl compound or the pharmacologically acceptable salt thereof； and use of the para-terphenyl compound or the pharmacologically acceptable salt thereof. (1) [wherein R1 and R2 independently represent an alkyl, cyclic alkyl, alkoxyalkyl, siloxyalkyl or phenyl group having 1 to 6 carbon atoms or an alkylene group having 3 or 4 carbon atoms； and R3 and R4 independently represent a hydrogen or a protective group for a hydroxyl group.] Thus, a compound having an inhibitory activity on the production of tumor necrosis factor (TNF)-a can be produced by a chemical synthesis. The compound has no toxic activity, and is therefore useful as a therapeutic agent for an autoimmune disease, an allergic disease or the like.
