ANTAGONISTES DE LA MOLECULE-1 ASSOCIEE A UNE LESION RENALE ET LEUR UTILISATION POUR MODULER LE SYSTEME IMMUNITAIRE

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专利权人:

BIOGEN IDEC MA INC.

发明人:

RENNERT, PAUL D.

申请号：

CA2512138

公开号：

CA2512138C

申请日:

2003.12.29

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

The use of KIM-1 antagonists to inhibit signaling between a T cell and asecond cell, e.g., an antigen-presenting cell, is disclosed. Such inhibitionis useful for treatment of diseases including various autoimmune diseases andgraft-versus-host disease. Also disclosed is the use of a KIM-1 antagonist toinhibit secretion of IFN-.gamma. by lymphocytes or other immune cells in amammal. Inhibition of IFN-.gamma. is useful for treatment of inflammatorydiseases or disorders, e.g., inflammatory bowel disease.

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http://www.ckcest.cn/home/