MARLOW, ALLISON L.,YANG, HONG WOON,SEO, JEONGBEOB,LYSSIKATOS, JOSEPH P.,WALLACE, ELI,BLAKE, JIM
申请号:
HK11104718.0
公开号:
HK1150607B
申请日:
2011.05.13
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R 1 , R 2 , R 7 , R 8 and R 9 , W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.