Inhibitors of A-Beta and synuclein aggregation

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专利权人:

The Feinstein Institute for Medical Research

发明人:

Al-Abed, Yousef

申请号：

AU2007265631

公开号：

AU2007265631B2

申请日:

2007.06.22

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Provided are methods of inhibiting aggregation of amyloid-beta (Aβ)or accumulation of aggregated Aβ using certain guanylhydrazone compounds.Also provided are methods of treating or preventing an amyloid-related diseasein a mammal, methods of treating a subject having Alzheimer's disease,methods of treating a subject at risk for Alzheimer's disease, methodsof inhibiting aggregation or accumulation of a synuclein, methods of treatinga subject having a disease at least partially mediated by synuclein, methodsof treating a subject at risk for a disease at least partially mediated by synuclein,and methods of inhibiting aggregation or accumulation of a protein involvedin a conformational disease, using the guanylhydrazone compounds.

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中国工程科技知识中心

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