H. Lee Moffitt Cancer Center And Research Institute, Inc.;The Wistar Institute
发明人:
申请号：
EP16790217.0
公开号：
EP3291842A4
申请日:
2016.05.07
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The invention concerns a variant (double mutant form) of the survivin polypeptide； nucleic acid molecules encoding the survivin variant； antigen presenting cells (APCs) such as dendritic cells, or APC precursors, comprising the variant survivin polypeptide or encoding nucleic acid sequence； and methods for treating a malignancy, such as myeloma, or for inducing an immune response, utilizing a variant survivin polypeptide, nucleic acid molecule, or APC.
