PROBLEM TO BE SOLVED: To provide an improvement agent for FD (functional dyspepsia), particularly upper abdomen discomfort such as nausea caused by deterioration in gastric emptying ability due to stress.SOLUTION: The functional dyspepsia improvement agent is provided which contains, as an active ingredient, an azulene derivative represented by the general formula (I) (in the formula (I), R1 represents an alkyl group having a carbon number of 1 to 6 and R2 and R3 each independently represent a hydrogen atom or an alkyl group having a carbon number of 1 to 6). An anti-stress-related gastric emptying retardation improvement agent is also provided which contains the azulene derivative represented by the general formula (I) as an active ingredient.COPYRIGHT: (C)2015,JPO&INPIT【課題】FD(機能性胃腸症)、特にストレスによる胃排泄能が低下して引き起こされる悪心等の上腹部不快感の改善剤の提供。【解決手段】下記一般式(I)(式(I)中、R1は炭素数1~6のアルキル基を表し、R2及びR3は、それぞれ独立して、水素原子又は炭素数1~6のアルキル基を表す。)で表されるアズレン誘導体を有効成分とすることを特徴とする、機能性胃腸症改善剤、及び前記一般式(I)で表されるアズレン誘導体を有効成分とすることを特徴とする、抗ストレス性胃排泄遅延症改善剤。[化1]【選択図】なし
