Methods for making foamed adhesive compositions suitable for use in adhesive dressings for topical application to the body, the method including providing a molten adhesive composition, combining an inert gas with the molten adhesive composition in a first mixer, mixing the molten adhesive composition comprising the inert gas in the first mixer under conditions effective to form a first foamed adhesive composition； and mixing the first foamed adhesive composition in a second mixer that includes a rotating mixing blade under conditions effective to provide a second foamed adhesive composition having a substantially homogenous distribution of closed cells containing the inert gas.
