K. Dane Wittrup,Jeffrey Ravetch,Stephen Lael Sazinsky
申请号：
US12746411
公开号：
US08815237B2
申请日:
2008.12.05
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention is based, in part, on our discovery of immunoglobulins (e.g., immunoglobulin G (IgG)) polypeptides (e.g., murine or human IgG, such as human IgG1) that are aglycosylated yet retain the ability to bind to an Fc receptor, such as an activating Fc receptor (e.g., FcγRIIA and/or FcγRIIIA).
