Aglycosylated immunoglobulin mutants

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专利权人:

发明人:

申请号：

EP14167580.1

公开号：

EP2808345A2

申请日:

2008.12.05

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention is based, in part, on our discovery of immunoglobulins (e.g., immunoglobulin G (IgG)) polypeptides (e.g., murine or human IgG, such as human IgG1) that are aglycosylated yet retain the ability to bind to an Fc receptor, such as an activating Fc receptor (e.g., Fcy RIIA and/or FcyRIIIA).

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