YAN, GUANGMEI,HU, HAIYAN,ZHANG, JINGXIA,QIU, PENGXIN,LI, LING,TIAN, NING
申请号：
CA2809646
公开号：
CA2809646C
申请日:
2011.07.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A 5a-androstane (alkyl)-3ß,5,6ß-triol injection and preparation method therefor, the injection whereof using hydroxypropyl-ß-cyclodextrin as a solubilizer and the active ingredient whereof being present preferably in a proportion by weight of 1-20:40-500 to the cyclodextrin. The injection may also comprise 1-100 parts of an isotonic regulator, 0-200 parts of a lyophilized filler, 0-2000 parts of a solvent. The preparation method comprises separately and successively dissolving the hydroxypropyl-ß-cyclodextrin solution, the active ingredient and other soluble accessory ingredients in the water for injection, then after decolorization, depyrogenation, filtering, and sterilization of the filtrate, a liquid injection solution is obtained. Drying the filtrate yields a solid for injection.
