The surface of the body insertion portion, the manufacturing method of antimicrobial medical device of the present invention, an antimicrobial agent-containing to disperse the antimicrobial agent particles in a solvent mixture with the first solvent and the second solvent having a boiling point at least different medical devices and characterized in that it comprises a drying step of drying the adhesion step of adhering solvent, the solvent-containing antibacterial agent attached to the surface of the medical device.本発明の抗菌性医療器具の製造方法は、医療器具の少なくとも体内挿入部位の表面に、沸点が異なる第1溶媒と第2溶媒とを混合した混合溶媒に抗菌剤粒子を分散させた抗菌剤含有溶媒を付着させる付着工程と、前記医療器具の表面に付着した前記抗菌剤含有溶媒を乾燥させる乾燥工程と、を含むことを特徴とする。