Cleaning and disinfection stick is designed in the manner of a nylon toothpick. In contrast to a toothpick, it is arcuate over its length, wherein straight embodiments are also possible. It tapers from its remaining diameter into a fine tip in at least one of its ends regions. Adjacent to the fine tip, the stick can include a round brush. Alternatively, it can also include a felt-like, textile or fluffy surface or be provided with a rod-like paper or plastic attachment. After removing a piercing, it can be inserted, leading with the fine tip into the skin hole and subsequently be pushed further into the skin hole until its cleaning body is inserted therein. It is then gently moved to and fro or rolled to and fro about its axis and pulled out again.