5- [2- (PYRIDIN-2-YLAMINO) -1,3-THIAZOL-5-YL] -2,3-DIHYDRO-1H-ISOINDOL-1-UNDERIVATIVES AND THEIR USE AS DOUBLE INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE DELTA & GAMMA

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专利权人:

Astrazeneca

发明人:

PERRY, Matthew,KARABELAS, Konstantinos,MOGEMARK, Mickael,BOLD, Peter,TYRCHAN, Christian,NIKITIDIS, Antonios,PETERSEN, Jens,BÖRJESSON, Ulf

申请号：

DK17772381

公开号：

DK3515910T3

申请日:

2017.09.21

申请国别(地区):

DK

年份:

2020

代理人:

摘要：

There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof) (I) that inhibit phosphatidylinositol 3-kinase gamma (PI3Kδ) and phosphatidylinositol 3-kinase gamma (ΡΙ3Κγ) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

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