5-[2-(PYRIDIN-2-YLAMINO)-1,3-THIAZOL-5-YL]-2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND THEIR USE AS DUAL INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE DELTA and GAMMA

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专利权人:

ASTRAZENECA AB

发明人:

PERRY, Matthew,KARABELAS, Konstantinos,MOGEMARK, Mickael,BOLD, Peter,TYRCHAN, Christian,NIKITIDIS, Antonios,PETERSEN, Jens,B™RJESSON, Ulf

申请号：

PH12019500615

公开号：

PH12019500615A1

申请日:

2019.03.21

申请国别(地区):

PH

年份:

2019

代理人:

摘要：

There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof) (I) that inhibit phosphatidylinositol 3-kinase gamma (PI3Kd) and phosphatidylinositol 3-kinase gamma (??3??) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

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