GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
BI, MEIXIA,HOPSON, CHRISTOPHER B.,MAYES, PATRICK A.,YADAVILLI, SAPNA
申请号：
CA3066048
公开号：
CA3066048A1
申请日:
2018.06.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides methods of treating cancer in a patient in needthereof, the method comprising administeringto the patient an effective amount of an agent directed to human ICOS and aneffective amount of an agent directed to humanPD 1 or human PD-Ll sequentially. The present invention also provides an anti-ICOS antibody or antigen binding fragment thereofand an anti-PD 1 antibody or antigen binding fragment thereof for sequentialuse in treating cancer in a human in need thereof. Thepresent invention provides an anti- ICOS antibody or antigen binding fragmentthereof and an anti-PD-Ll antibody or antigen bindingfragment thereof for sequential use in treating cancer in a human in needthereof.
