GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
HOPSON, CHRISTOPHER B.,KILIAN, DAVID J.,MAYES, PATRICK A.,YADAVILLI, SAPNA,YANAMANDRA, NIRANJAN
申请号：
CA3066007
公开号：
CA3066007A1
申请日:
2018.06.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides methods of treating cancer in a patient in needthereof, the method comprisingadministering to the patient an effective amount of an agent directed to humanICOS and an effective amount of an agent directed to humanOX40 sequentially. The present invention also provides an anti-ICOS antibodyor antigen binding fragment thereof and an anti-OX40antibody or antigen binding fragment thereof for sequential use in treatingcancer in a human in need thereof.
