CHERNOVSKAYA TATYANA VENIAMINOVNA,CHERNOVSKAYA TATYANA VENIAMINOVNA,DENISOV LEV ALEXANDROVICH,RUDENKO ELENA GEORGIEVNA,MOROZOVA ELENA LEONIDOVNA
申请号：
IN928/CHENP/2013
公开号：
IN2013CN00928A
申请日:
2013.02.05
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to pharmaceuticals and medicine, namely, to new physiologically active conjugates of granulocyte colony-stimulating factor (G-CSF) with the general formula (I) where: n - integers from 681 to 1 000 m - integer > 4 NαH-G-CSF - natural or recombinant polypetide, having the activity of G-CSF. The invention is also related to medicines containing the claimed conjugate of formula (I), pharmaceutical compositions, the use of conjugate of formula (I) for drugs and medicines with granulocyte colony stimulating factor as an active ingredient, approaches to prevent and / or treat neutropenia, the container that comprises pharmaceutical composition.
