CHERNOVSKAYA TATYANA VENIAMINOVNA,MOROZOV DMITRIY VALENTINOVICH,DENISOV LEV ALEXANDROVICH,RUDENKO ELENA GEORGIEVNA,KLENOVA ANGELINA VSEVOLODOVNA
申请号：
CU20130012
公开号：
CU24139B1
申请日:
2013.01.18
申请国别(地区):
CU
年份:
2015
代理人:
摘要：
The present invention relates to pharmaceuticals and medicine, namely, to new physiologically active conjugates of granulocyte colony-stimulating factor (G-CSF) with the general formula (I) where: n - integers from 681 to 1 000； m - integer >； 4； NaH-G-CSF - natural or recombinant polypetide, having the activity of G-CSF. The invention is also related to medicines containing the claimed conjugate of formula (I), pharmaceutical compositions, the use of conjugate of formula (I) for drugs and medicines with granulocyte colony stimulating factor as an active ingredient, approaches to prevent and / or treat neutropenia, the container that comprises pharmaceutical composition.
