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Methods of treatment using lipid compounds
专利权人:
Ragnar Hovland;Tore Skjæret;David Fraser
发明人:
Ragnar Hovland,Tore Skjæret,David Fraser
申请号:
US13883405
公开号:
US09394228B2
申请日:
2011.11.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Methods are disclosed to treat or prevent at least one disease or condition in a subject in need thereof comprising administering a compound of Formula (I):or a pharmaceutically acceptable salt, or ester thereof,wherein R1 and R2 are independently chosen from a hydrogen atom or linear, branched, and/or cyclic C1-C6 alkyl groups, with the proviso that R1 and R2 are not both hydrogen or a pharmaceutically acceptable salt or ester thereof. Such diseases or conditions may relate to coronary heart disease (CHD), for example atherosclerosis; metabolic syndrome/insulin resistance; and/or a dyslipidemic condition such as hypertriglyceridemia (HTG), elevated LDL-cholesterol, elevated total-cholesterol, elevated Apo B and low HDL-cholesterol.The present disclosure further provides for a method of reducing atherosclerosis development. Pharmaceutical compositions comprising a compound of Formula (I) are also disclosed.
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