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METHODS OF TREATMENT USING LIPID COMPOUNDS
专利权人:
PRONOVA BIOPHARMA NORGE AS
发明人:
HOVLAND RAGNAR,FRASER DAVID A,SKJAERET TORE
申请号:
ZA201303813
公开号:
ZA201303813B
申请日:
2013.05.24
申请国别(地区):
ZA
年份:
2015
代理人:
摘要:
Methods are disclosed to treat or prevent at least one disease or condition in a subject in need thereof comprising administering a compound of Formula (I): or a pharmaceutically acceptable salt, or ester thereof, wherein R1 and R2 are independently chosen from a hydrogen atom or linear, branched, and/or cyclic C1-C6 alkyl groups, with the proviso that R1 and R2 are not both hydrogen or a pharmaceutically acceptable salt or ester thereof. Such diseases or conditions may relate to coronary heart disease (CHD), for example atherosclerosis; metabolic syndrome/insulin resistance; and/or a dyslipidemic condition such as hypertriglyceridemia (HTG), elevated LDL-cholesterol, elevated total-cholesterol, elevated Apo B and low HDL-cholesterol. The present disclosure further provides for a method of reducing atherosclerosis development. Pharmaceutical compositions comprising a compound of Formula (I) are also disclosed.
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中国工程科技知识中心
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