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包衣製劑及其製造方法
专利权人:
LION CORPORATION
发明人:
TAKAHASHI, CHIAKI,高桥千晶,高橋千晶,MATSUNO, AYUMI,松野步,KIZU, NORIO,木津典生
申请号:
TW104129219
公开号:
TW201625308A
申请日:
2015.09.03
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
Provided are: a coated preparation which cannot be dissolved in the stomach but can be dissolved in the intestine to ensure a coated active ingredient to reach the intestine, and can be prevented expeditiously from being deteriorated over time, and has excellent storage stability; and a method for producing the coated preparation. A coated preparation comprising: a substance to be coated; an under layer which is formed on the substance and contains a polymeric compound (A) having such a property that an aqueous 6 mass% solution has a viscosity of less than 300 mPas at 25 DEG C; and an enteric coating layer which is formed on the under layer and contains an alginate salt (B) and a plasticizer (C).本發明係提供在胃中不溶而在腸中溶解,不僅可使經包覆之有效成分更確實地到達至腸,並能夠盡可能地抑制經時劣化,保存安定性亦優異的包衣製劑及其製造方法。一種包衣製劑,其特徵為具有被包覆物、在其上所形成之下層及在該下層上所形成之腸溶性包覆層;該下層包含(A)6質量%水溶液之於25℃之黏度係未滿300mPa.s的高分子化合物;該腸溶性包覆層包含(B)海藻酸鹽及(C)可塑劑。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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