Isolated OMP106 polypeptide, gene sequence, antibody and vaccine
- 专利权人:
- ANTEX BIOLOGICS, INC.
- 发明人:
- TUCKER KENNETH,PLOSILA LAURA
- 申请号:
- CZ19980003524
- 公开号:
- CZ298034(B6)
- 申请日:
- 1997.04.28
- 申请国别(地区):
- 捷克
- 年份:
- 2007
- 代理人:
- 摘要:
The present invention relates to Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding said polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally relates to immunogenic, prophylactic or therapeutic compositions including vaccines containing the OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals.
- 来源网站:
- 中国工程科技知识中心
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- Isolated OMP106 polypeptide or fragment thereof, vaccine and antigenic composition comprising thereof, isolated DNA, isolated antibody and their use