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Isolated OMP106 polypeptide, gene sequence, antibody and vaccine
专利权人:
ANTEX BIOLOGICS, INC.
发明人:
TUCKER KENNETH,PLOSILA LAURA
申请号:
CZ19980003524
公开号:
CZ298034(B6)
申请日:
1997.04.28
申请国别(地区):
捷克
年份:
2007
代理人:
摘要:

The present invention relates to Moraxella catarrhalis outer membrane protein-106 (OMP106) polypeptide, polypeptides derived therefrom (OMP106-derived polypeptides), nucleotide sequences encoding said polypeptides, and antibodies that specifically bind the OMP106 polypeptide and/or OMP106-derived polypeptides. Also disclosed are immunogenic, prophylactic or therapeutic compositions, including vaccines, comprising OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally relates to immunogenic, prophylactic or therapeutic compositions including vaccines containing the OMP106 polypeptide and/or OMP106-derived polypeptides. The invention additionally discloses methods of inducing immune responses to M. catarrhalis and M. catarrhalis OMP106 polypeptides and OMP106-derived polypeptides in animals.

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