Syringe assemblies including a syringe pre-equipped with an integral liquid drug administration device for enabling administration of liquid drug contents and a drug vial adapter for telescopic mounting on a drug vial containing liquid drug contents. The drug vial adapter is initially mounted on the syringe and is intended to be manually detached therefrom to expose the integral liquid drug administration device. The syringe includes a flow control member having an initial flow path position for enabling filling the syringe with liquid drug contents from the drug vial and a final flow path position for enabling administration of liquid drug contents. Detachment of the drug vial adapter from the syringe urges the flow control member from its initial flow path position to its final flow path position.
