Diastereomers of the 10-propargyl-10-deazaaminopterin FOR USE IN THE TREATMENT OF CANCER

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专利权人:

Allos Therapeutics; Inc.

发明人:

PRONK, Gijsbertus, J.

申请号：

DK10845390

公开号：

DK2531193T3

申请日:

2010.03.04

申请国别(地区):

DK

年份:

2016

代理人:

摘要：

The present invention relates to diastereomers of 10-propargyl-10-deazaminopterin, compositions comprising optically pure diastereomers of 10-propargyl-10-deazaminopterin, in particular the two (R,S) diastereomers about the C10 position. Methods of preparation of these diastereomers, compositions containing them, and their use for the treatment of conditions related to inflammatory disorders and cancer are also disclosed.

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