DIASTÉRÉO-ISOMÈRES OPTIQUEMENT PURS DE 10-PROPARGYL-10-DEAZAAMINOPTÉRINE, ET LEURS PROCÉDÉS D'UTILISATION

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专利权人:

INC.;ALLOS THERAPEUTICS

发明人:

PRONK, GIJSBERTUS, J.

申请号：

EP10845390

公开号：

EP2531193A4

申请日:

2010.03.04

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to diastereomers of 10-propargyl-10-deazaminopterin, compositions comprising optically pure diastereomers of 10-propargyl-10-deazaminopterin, in particular the two (R,S) diastereomers about the C10 position. Methods of preparation of these diastereomers, compositions containing them, and their use for the treatment of conditions related to inflammatory disorders and cancer are also disclosed.

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