Michael J. Breslin,Paul J. Coleman,Christopher D. Cox,Izzat T. Raheem,John D. Schreier
申请号:
US13389270
公开号:
US20120136012A1
申请日:
2010.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to amino tetrahydro-pyridopyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntingtons disease, and those associated with striatal hypofunction or basal ganglia dysfunction.