Pablo DeLeon,Melissa Egbertson,Ivory D. Hills,Adam Wayne Johnson,Michelle Machacek
申请号:
US13384946
公开号:
US08680116B2
申请日:
2010.07.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to quinolinone compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntingtons disease, and those associated with striatal hypofunction or basal ganglia dysfunction.