Robert O. WILLIAMS, III,Hiroyuki TAKABE,Daniel Alan DAVIS,Zachary WARNKEN
申请号:
US16646452
公开号:
US20200206139A1
申请日:
2018.09.11
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Pharmaceutical compositions for improving the solubility and dissolution of poorly soluble drugs which contain a therapeutic agent, a pharmaceutically acceptable polymer, and a spontaneously emulsifying component are described herein. These pharmaceutical compositions have been prepared by thermal processes to obtain a composition which shows improved properties including improved solubility of the therapeutic agent above the amount of therapeutic agent which should be soluble in either the spontaneously emulsifying component or the pharmaceutically acceptable polymer. Also provided herein are methods of preparing and use thereof.