Jeffrey D. Milbrandt,Aaron DiAntonio,Kow Essuman,Xianrong Mao,Yo Sasaki,Dan Summers
申请号:
US16651196
公开号:
US20200283820A1
申请日:
2018.09.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides compounds useful as inhibitors of TIR NADase activity, compositions thereof, and methods of using the same. The present invention is useful for inhibition of TIR-domain NADase activity and/or treating microbial infection and/or modulating microbial physiology.