ATTENUATED SWINE INFLUENZA VACCINES AND METHODS OF MAKING AND USE THEREOF

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专利权人:

MERIAL LIMITED

发明人:

HAUSE, Benjamin, M

申请号：

PH12015500095

公开号：

PH12015500095A1

申请日:

2015.01.14

申请国别(地区):

PH

年份:

2015

代理人:

摘要：

This disclosure provides attenuated swine influenza strains, particularly those produced via a reverse genetics approach, compositions comprising same, and methods of production and use thereof. The attenuated strains are engineered to encode HA proteins having additional glycosylation sites, relative to the HA proteins encoded by the corresponding virulent parental viruses. Advantageously, the attenuated influenza strains may be administered

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