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Attenuated swine influenza vaccines and methods of making and use thereof
专利权人:
Benjamin M Hause
发明人:
Benjamin M Hause
申请号:
US13939321
公开号:
US09216211B2
申请日:
2013.07.11
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This disclosure provides attenuated swine influenza strains, particularly those produced via a reverse genetics approach, compositions comprising same, and methods of production and use thereof. The attenuated strains are engineered to encode HA proteins having additional glycosylation sites, relative to the HA proteins encoded by the corresponding virulent parental viruses. Advantageously, the attenuated influenza strains may be administered.
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中国工程科技知识中心
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