SCHOLZ, MATTHEW REIN,HERBIG, ERIC J.,MCIVOR R., SCOTT,DE LAAT, RIAN,OLSON, ERIK
申请号:
CA3061048
公开号:
CA3061048A1
申请日:
2018.04.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to methods for administering autologous and/or allogeneic B cells genetically modified to produce a therapeutic agent, such as a therapeutic protein. Specifically disclosed are methods for administering a single, maximally effective dose of genetically modified B cells and for administering multiple doses of genetically modified B cells. The compositions and methods disclosed herein are useful for the long-term, in vivo delivery of a therapeutic agent.