Methods of colchicine administration

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专利权人:

发明人:

Murray Ducharme

申请号：

US14511703

公开号：

US09675613B2

申请日:

2014.10.10

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention provides improved methods for coadministration of colchicine with drugs metabolized by CYP3A4 (anciently referred to as cytochrome P450 isozyme 3A4) or the P-glycoprotein transporter, but not both. The method enables non-toxic coadministration of colchicine and the second drug at their ordinary levels safely and effectively without reducing the dose or frequency for either drug.

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