the present invention relates to a process for preparing a powder formulation for inhalation for use in a dry powder inhaler, said powder comprising: (a) a carrier comprising: (a) 80 to 95 percent by weight, based on in the total weight of said carrier, of coarse particles of a physiologically acceptable excipient having an average particle size of at least 175 microns； and (b) 19.6 to 4.9 percent by weight, based on the total weight of said carrier, of micronized particles of a physiologically acceptable excipient, and (c) 0.1 to 0.4 percent by weight, based on the total weight of said carrier, of a fatty acid salt； and (b) micronized particles of glycopyrronium bromide, a long-acting o2 agonist (lab) and an inhaled corticosteroid (ics), as active ingredients, said process comprising: (i) preparation by co-grinding of microparticles consisting of glycopyrronium and a first part of an ics in a proportion ranging from 80:20 to 70:30 by weight, where the volumetric diameter of said microparticles is not more than 15 microns； (ii) mixing of the coarse particles of a physiologically acceptable excipient, the salt of a fatty acid, a first part of said micronized particles of a physiologically acceptable excipient, the micronized particles of said lab, the co-crushed microparticles obtained in step (i), and the remaining parts of said ics in a container of a stirrer at a rotation speed of not less than 16 rpm for a time of not less than 60 minutes, to obtain a first mixture； and (iii) adding the remaining part of the micronized particles of a physiologically acceptable excipient to said mixture to obtain a second mixture, and mixing said second mixture at a speed of rotation of not less than 16 rpm for a time of at least 120 minutes to get a formulation.a presente invenção se refere a um processo para preparar uma formulação em pó para inalação para uso em um inalador de pó seco, o referido pó compreendendo: (a) um carreador compreendendo: (a) 80 a 95 por cento por peso,
