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Compositions for the reversible thioesterification of signaling proteins and methods of using same
专利权人:
Jonathan S. Stamler
发明人:
Jonathan S. Stamler,Jordan Gutterman
申请号:
US11488992
公开号:
US08853168B2
申请日:
2006.07.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Avicins and other thioesterification agents are used to modify cysteine groups of signaling proteins in order to modify their activity. Pathologies associated with signaling proteins which are regulatable through this method are treated using these thioesterification agents. These pathologies include those involving proteins which modulate physiologic redox status of organisms including arthersclerosis, cancer, bacterial infection, inflammation, and neurological disorders.
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中国工程科技知识中心
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