COMPOSITIONS FOR THE REVERSIBLE THIOESTERIFICATION OF SIGNALING PROTEINS AND METHODS OF USING SAME

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专利权人:

DUKE UNIVERSITY

发明人:

STAMLER, JONATHAN S.,GUTTERMAN, JORDAN

申请号：

CA2616589

公开号：

CA2616589C

申请日:

2006.07.18

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Avicins and other thioesterification agents are used to modify cysteine groupsof signaling proteins in order to modify their activity. Pathologiesassociated with signaling proteins which are regulatable through this methodare treated using these thioesterification agents. These pathologies includethose involving proteins which modulate physiologic redox status of organismsincluding arthersclerosis, cancer, bacterial infection, inflammation, andneurological disorders.

来源网站：

中国工程科技知识中心

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