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A SELF-EMULSIFYING COMPOSITION FOR POORLY BIOAVAILABLE DRUGS
专利权人:
HOVID BERHAD
发明人:
NG, BEE, HONG,CHOY, WAI, PENG,WONG, JIA, WOEI,KHOO, JUNE, LAY, CHOO,HO, DAVID, SUE, SAN,YUEN, KAH, HAY
申请号:
NZ57277107
公开号:
NZ572771A
申请日:
2007.06.15
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a drug delivery formulation comprising (a) an edible and pharmaceutically acceptable fatty acid e.g. oleic acid, eleostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, elaidic acid, linoleic acid, and docosahexaenoic acid. (b) a non-ionic surfactant e.g. polyoxyethylene (20) sorbitan monooleate, polyoxyethylene (20) sorbitan monostearate, glyceryl polyethylene glycol oxystearate, glycerol polyethylene glycol ricinoleate, sucrose stearate, sucrose oleate, sucrose palmitate, sucrose myristate, sucrose laurate, decaglycerollauric acid esters, decaglycerol myristic acid esters, decaglycerol stearic acid esters. and (c) a drug wherein components (a) and (b) are miscible with each other and are in an isotropic mixture in a ratio ranging from 9.5:0.5 w/w to 9: 1 w/w and wherein neither a co-solvent nor an adjuvant is present in the formulation.
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