WEIGANDT, MARKUS,HANEFELD, ANDREA,KUEBELBECK, ARMIN,LARBIG, GREGOR
申请号：
CA2730694
公开号：
CA2730694C
申请日:
2009.07.13
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention relates to ultra-small, monodisperse nanoparticles of silicondioxide with atleast one antigen attached to their surface. The nanoparticles can be used fortheimmunoprophylaxis or immunotherapy of cancer. The invention also provides amethodof targeting antigens at antigen-presenting cells and of activating the immunesystem, theefficiency of targeting and/or immune activation being adjusted via theparticlecharacteristics. The invention also relates to methods of active and passiveimmunizationof a mammal.
