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SUBSTITUTED PIPERIDINE SPIRO PYRROLIDINONE AND PIPERIDINONES USED AS H3 MODULATORS
专利权人:
SANOFI
发明人:
HALL DANIEL,HARTUNG RYAN,GAO ZHONGLI
申请号:
TN2011000233
公开号:
TN2011000233A1
申请日:
2011.05.11
申请国别(地区):
TN
年份:
2012
代理人:
摘要:
The present invention discloses and claims a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I), wherein R1, R2, R3, m, n and p are as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, this invention also discloses methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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