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Substituted piperidine spiropyrrolidinone and piperidinone used as H3 modulators
专利权人:
サノフイ
发明人:
チョンリー・ガオ,ダニエル・ホール,リャン・ハルトゥング
申请号:
JP2011539716
公开号:
JP5538421B2
申请日:
2009.12.04
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
The present disclosure relates to a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I). wherein R1, R2, R3, m, n and p are as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefor are disclosed.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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