(57)< Abstract > (A) petoroserin acid and/or that derivative and, (b) rechinoido and/or the LRAT/ARAT inhibiter and, (c) skin the composition for section which consists of with the vehicle which is allowed scientifically. As for this kind of skin protective composition, the wrinkle and the sag, the optical damage skin and the dry skin, it is typical is selected from the group which consists of old person unevenness, but remedy of desirable skin state and/or it is effective to the quiet of prevention, and the sensitive skin.(a)ペトロセリン酸及び/またはその誘導体と、(b)レチノイド及び/またはLRAT/ARATインヒビターと、(c)皮膚科学的に許容されるビヒクルとから成る局所用組成物。このような皮膚保護組成物は、皺、たるみ、光損傷肌、乾燥肌、老人斑から成るグループから選択された典型的ではあるが望ましくない皮膚状態の治療及び/または予防、並びに、敏感肌の鎮静に有効である。
