PROBLEM TO BE SOLVED: To provide compositions having fatty acid binding protein (FABP) 5 production inhibitory action that causes atherosclerosis and diabetes, and worsens skin conditions such as reduced barrier function and inflammation.SOLUTION: Provided is a composition for inhibiting FABP5 production comprising as an active ingredient one or more substances selected from nobiletin, naringin, sulforaphane, homoorientin, methyl jasmonate contained in a Citrus unshiu Markovich extract and/or a Citrus tachibana extract or broccoli extract.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】粥状動脈硬化や糖尿病を発症させたり、バリア機能低下や炎症など肌状態を悪化させたりする脂肪酸結合タンパク質(FABP)5産生抑制作用を有する組成物の提供。【解決手段】チンピエキス及び/又はキッピエキスやブロッコリー抽出物に含まれるノビレチン、ナリンギン、スルフォラファン、ホモオリエンチン、ジャスモン酸メチルから選択される1以上の物質を有効成分として含むFABP5産生抑制用組成物。【選択図】なし