abstract the present inventors created antigen-binding molecules containing an antigen-binding domain and an fc? -receptor-binding domain, wherein the molecules have human-fcrn-binding activity in an acidic ph range condition, the antigen-binding domain changes the antigen -binding activity of the antigen-binding molecules depending on the ion-concentration condition, and the fc? receiver-binding domain has higher binding activity to the fc? receptor in a neutral ph range condition of a region of a native human igg in which the sugar chain bound at position 297 (eu numbering) is a fucose-containing sugar chain. changes from the specification of wo2013 / 047729 (our ref .: c1-a1110p) to that of wo2013 / 047752 (our ref .: c1-a1111p). unchanged parts are shown in black. changes in the tables are not shown. This document is provided solely for your reference and convenience. when preparing a translation, please refer to and literally translate the english specification into your language. -------------------------------------------------- ------------------------ Translation of abstract patent summary: "Antigen-binding molecule for promoting antigen loss". The present invention relates to antigen-binding molecules containing an antigen-binding domain and an Î ± 1 receptor binding domain, where the molecules have human Î ± f-binding activity in an acidic ph-band condition. the antigen binding domain changes the antigen binding activity of antigen binding molecules depending on the ion concentration condition, and the fc? Do you have higher fc receptor binding activity? in a neutral ph range condition than a fc region of a native human igg where the sugar chain linked at position 297 (eu numbering) is a fucose containing sugar chain.abstract the present inventors created antigen-binding molecules containing an antigen-binding domain and an fc?-receptor-binding domain, wherein the molecules have human-fcrn-binding activity in an acidic ph range condition, the antigen-bind
