David W. Borhani,Ramkrishna Sadhukhan,Susan E. Lacy,Holly H. Soutter
申请号:
US13374693
公开号:
US20120288494A1
申请日:
2012.01.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides antibodies, and antigen-binding portions thereof, that bind to epitopes comprising at least one amino acid residues from residues 1-197 of the p40 subunit of IL-12 and/or IL-23. The invention further provides nucleic acids encoding the antibodies, compositions, vectors and host cells comprising the antibodies, and methods of making and using the same.