DAVID W. BORHANI,HOLLY H. SOUTTER,RAMKRISHNA SADHUKHAN,SUSAN E. LACY
申请号:
BR112013017417
公开号:
BR112013017417A2
申请日:
2012.01.06
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention provides antibodies, and antigen-binding portions thereof, that bind to epitopes comprising at least one amino acid residues from residues 1-197 of the p40 subunit of IL-12 and/or IL-23. The invention further provides nucleic acids encoding the antibodies, compositions, vectors and host cells comprising the antibodies, and methods of making and using the same.