The invention relates to a local stimulation method of a predetermined region of brain tissue, said brain tissue comprising at least GABAergic neuron type. According to the invention, said method comprises at least one activation step (10) of a set of bipolar electrodes (SBE), according to a predetermined electric intensity (PEI) and a predetermined -biphasic pulse frequency (PBPF), delivering a predetermined electric field (PEF), said predetermined electric field (PEF) inducing an activation of said GABAergic type neurons and a virtual absence of activation of other types of neurons.