ALDERBORN, Goran,FORSLUND, Anders,HOLMBACK, Ulf,LENNERNAS, Hans,GRUDEN, Jan Stefan Persson
申请号：
PH12017550023
公开号：
PH12017550023A1
申请日:
2017.06.02
申请国别(地区):
PH
年份:
2017
代理人:
摘要：
The present invention relates to a modified-release composition comprising orlistat and acarbose, comprising individually distinct parts with different release patterns: a) a first part, G1, comprising from about 5 to about 70 pcnt w/w of the total dose of acarbose, b) a second part, G2A, comprising from about 30 to about 95 pcnt w/w of the total dose of acarbose, c) a third part, G2B, comprising from about 10 to about 90 pcnt w/w of the total dose of orlistat, and d) a fourth part, G3, comprising from about 10 to about 80 pcnt w/w of the total dose of orlistat, and the total concentration of acarbose and orlistat, respectively, in the composition is 100 pcnt w/w.
