N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

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专利权人:

Novartis AG

发明人:

CHEN Christine Hiu-tung,CHEN Christine Hiu-tung,CHEN Zhuoliang,CHEN Zhuoliang,DORE Michael,DORE Michael,FORTANET Jorge Garcia,FORTANET Jorge Garcia,KARKI Rajesh,KARKI Rajesh,KATO Mitsunori,KATO Mitsun

申请号：

SI201530432

公开号：

SI3094628T1

申请日:

2015.01.16

申请国别(地区):

SI

年份:

2018

代理人:

摘要：

in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/